Journal: Human Brain Mapping
Article Title: Motor mapping of the hand muscles using peripheral innervation‐based navigated transcranial magnetic stimulation to identify functional reorganization of primary motor regions in malignant tumors
doi: 10.1002/hbm.26642
Figure Lengend Snippet: Workflow of the study. This figure presents the workflow of the current study. It consists of a cortical and subcortical part. In the yellow box, group 1 (patients with tumors inside the left corticospinal tract [CST] or precentral gyrus, G1) and group 2 (patients with tumors outside the left CST or precentral gyrus, G2) are defined by whether tumors are within or outside primary motor regions. In the green box, their T1 images with contrast (T1 + C) are applied for Navigated transcranial magnetic stimulation (nTMS) motor mapping, and the diffusion tensor imaging (DTI) files are imported to the Brainlab Element system for subcortical analysis (black box). According to different innervation, motor‐evoked potentials (MEPs) from other muscles are categorized into three groups. MEPs >50 mv are considered positive stimuli (PS). As shown in the gray box, PSs from the left abductor pollicis brevis muscle (APB) and flexor carpi radialis muscle (FCR) are grouped to median nerve‐related PSs (MPS), PSs from abductor digiti minimi muscle (ADM) are categorized as ulnar nerve‐related PSs (UPS), and all PSs are summarized as All PSs (APS). The cortical analysis of the center of gravity and mapping regions is depicted in the blue box. For the subcortical analysis in the black box, the areas of interest, respectively, from the MPS, UPS, and APS, are applied for the seed‐based fiber tracking analysis.
Article Snippet: MPS, UPS, and APS in DICOM format were imported into Brainlab Element (version 3.1.0; Brainlab AG, Munich, Germany) and set as seeds to fuse with T1 + C and DTI files.
Techniques: Diffusion-based Assay, Imaging, Muscles